Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690433 | 0.92 | ALDH1A1 (0.40) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8696610 | 0.80 | HTT (0.44) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8694583 | 0.75 | LMNA (0.39) | PDE3BPDE3AALDH1A1LMNAGLA | |
| SCHEMBL8690895 | 0.74 | HTT (0.42) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8690228 | 0.74 | ALDH1A1 (0.41) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8695782 | 0.73 | HTT (0.40) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8691277 | 0.73 | ALDH1A1 (0.47) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8693020 | 0.73 | ALDH1A1 (0.47) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL8689877 | 0.72 | HTT (0.40) | HTTPDE3BPDE3AALOX5ALDH1A1 | |
| SCHEMBL19618980 | 0.71 | ALDH1A1 (0.39) | HTTALDH1A1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |