Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693539 | 0.90 | FPR1 (0.37) | LMNAFPR1ALDH1A1FPR2KMT2A | |
| SCHEMBL8690998 | 0.88 | CNR2 (0.38) | FPR1ALDH1A1FPR2KMT2AL3MBTL1 | |
| SCHEMBL8691445 | 0.87 | CYP2C19 (0.48) | LMNAFPR1ALDH1A1FPR2KMT2A | |
| SCHEMBL8694845 | 0.86 | FPR1 (0.36) | FPR1ALDH1A1FPR2KMT2AL3MBTL1 | |
| SCHEMBL8691408 | 0.80 | FPR1 (0.42) | LMNAFPR1ALDH1A1FPR2KMT2A | |
| SCHEMBL9034552 | 0.80 | HPGD (0.48) | LMNAALDH1A1KMT2APDE4DMEN1 | |
| SCHEMBL8692841 | 0.80 | HRH1 (0.36) | FPR1FPR2SMN1; SMN2RAB9AHSP90AA1 | |
| SCHEMBL8693926 | 0.78 | HRH1 (0.35) | — | |
| SCHEMBL8696229 | 0.75 | TP53 (0.36) | SMN1; SMN2RAB9AMAPTTP53 | |
| SCHEMBL8690658 | 0.75 | HTT (0.41) | LMNAALDH1A1KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827863-A | Pyrazole derivatives as angiotensin II antagonists | J. URIACH & CIA, S.A. (ES) | 1998-10-27 | — | — | US | disclosed |
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |