Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697400 | 1.00 | TDP1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8693068 | 0.90 | RAB9A (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8691058 | 0.89 | ALDH1A1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9519178 | 0.89 | DPP8 (0.46) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9519172 | 0.88 | RAB9A (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9519405 | 0.88 | DPP8 (0.40) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10390103 | 0.86 | TDP1 (0.42) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL6398540 | 0.86 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL8759638 | 0.86 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL10364355 | 0.86 | TDP1 (0.43) | TDP1ATMALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756765-A | BACTERICIDES AND ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1998-05-26 | — | — | US | disclosed |
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |