SCHEMBL8690688

SCHEMBL8690688

CC(Oc1cccc(Cl)c1)C1CC(CCN(C)C)CCN1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 16/20 0.41
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8691256 0.99 GHSR (0.41) GHSRKDM4E
SCHEMBL8694229 0.87 SLC6A2 (0.35) GHSR
Hydrochloric Acid SCHEMBL8693208 0.86 SIGMAR1 (0.36) GHSR
SCHEMBL8690690 0.77 KDM4E (0.48) GHSRKDM4E
Hydrochloric Acid SCHEMBL8691258 0.77 KDM4E (0.47) GHSRKDM4E
SCHEMBL8691887 0.75 GHSR (0.42) GHSR
Hydrochloric Acid SCHEMBL8691113 0.74 SIGMAR1 (0.38) GHSR
Hydrochloric Acid SCHEMBL8693010 0.74 GHSR (0.42) GHSR
SCHEMBL8691890 0.67 KDM4E (0.44) GHSRKDM4E
SCHEMBL10991955 0.67 KDM4E (0.48) GHSRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5760035-A PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS KNOLL AKTIENGESELLSCHAFT (DE) 1998-06-02 US disclosed