Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | GHSR | Q92847 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8693208 | 0.99 | SIGMAR1 (0.36) | SLC6A2SLC6A4SLC6A3SIGMAR1GHSR | |
| Hydrochloric Acid SCHEMBL8691113 | 0.87 | SIGMAR1 (0.38) | SLC6A2SLC6A4SLC6A3SIGMAR1GHSR | |
| SCHEMBL8690688 | 0.87 | GHSR (0.41) | GHSR | |
| Hydrochloric Acid SCHEMBL8691256 | 0.86 | GHSR (0.41) | GHSR | |
| SCHEMBL8694232 | 0.75 | LTA4H (0.41) | SIGMAR1CYP1A2CYP3A4CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL8693211 | 0.74 | BLM (0.43) | SIGMAR1CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL8692200 | 0.72 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3SIGMAR1GHSR | |
| SCHEMBL8693727 | 0.69 | CYP1A2 (0.33) | SLC6A2SLC6A4SLC6A3SIGMAR1GHSR | |
| SCHEMBL8690690 | 0.65 | KDM4E (0.48) | GHSR | |
| Hydrochloric Acid SCHEMBL8691258 | 0.65 | KDM4E (0.47) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760035-A | PIPERIDINE COMPOUNDS SUBSTITUTED WITH AN AMINOALKYL GROUP AND AN ARYLOXYALKYL GROUP, ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, IMMUNOSUPPRESSANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-06-02 | — | — | US | disclosed |