Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689025 | 0.87 | P2RX7 (0.38) | LMNAMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL5232572 | 0.80 | MAPT (0.39) | LMNAMAPTL3MBTL1SMN1; SMN2CASP3 | |
| SCHEMBL7318709 | 0.78 | ALDH1A1 (0.39) | MAPTL3MBTL1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL8691614 | 0.77 | HDAC6 (0.45) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL8688564 | 0.74 | KDM4E (0.38) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL5238517 | 0.69 | ALDH1A1 (0.39) | LMNAMAPTL3MBTL1SMN1; SMN2CA12 | |
| SCHEMBL7330871 | 0.67 | ALDH1A1 (0.46) | LMNAMAPTL3MBTL1SMN1; SMN2CASP3 | |
| SCHEMBL7330866 | 0.67 | ALDH1A1 (0.46) | LMNAMAPTL3MBTL1SMN1; SMN2CASP3 | |
| SCHEMBL7241284 | 0.65 | KMT2A (0.49) | MAPTSMN1; SMN2TDP1KDM4EMEN1 | |
| SCHEMBL7241282 | 0.65 | KMT2A (0.49) | MAPTSMN1; SMN2TDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719278-A | TREATING EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-02-17 | — | — | US | disclosed |