Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5235254 | 0.79 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5234520 | 0.79 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5233480 | 0.75 | KMT2A (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL5233477 | 0.75 | KMT2A (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8691503 | 0.74 | DRD2 (0.39) | KDM4ENPSR1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19454419 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1KCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL5231836 | 0.68 | STING1 (0.38) | KDM4EL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11358481 | 0.65 | MAPT (0.55) | KDM4EL3MBTL1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31011703 | 0.64 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1MAPTSMN1; SMN2 | |
| SCHEMBL11048969 | 0.64 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719278-A | TREATING EXCESS RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-02-17 | — | — | US | disclosed |