Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690762 | 0.88 | IKBKB (0.37) | EPHX2IKBKBHIF1AEPAS1RARB | |
| SCHEMBL8691383 | 0.87 | PTPN1 (0.41) | EPHX2IKBKBHIF1AEPAS1PPARG | |
| SCHEMBL8570620 | 0.78 | IKBKB (0.31) | IKBKB | |
| SCHEMBL8397841 | 0.77 | EPHX2 (0.35) | EPHX2IKBKBHIF1AEPAS1RARB | |
| SCHEMBL8575216 | 0.74 | IKBKB (0.34) | EPHX2IKBKBHIF1AEPAS1RARA | |
| SCHEMBL8692338 | 0.73 | RARA (0.45) | IKBKBRARBRARGPPARGPPARA | |
| SCHEMBL8424159 | 0.72 | RARA (0.42) | IKBKBHIF1AEPAS1RARBRARG | |
| SCHEMBL8568404 | 0.72 | IKBKB (0.35) | EPHX2IKBKBHIF1AEPAS1RARB | |
| SCHEMBL8426205 | 0.72 | RARA (0.51) | IKBKBHIF1AEPAS1RARBRARG | |
| SCHEMBL8574908 | 0.71 | IKBKB (0.33) | IKBKBHIF1AEPAS1RARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | claimed |
| US-5786379-A | Adamantyl-substituted biaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 1998-07-28 | — | — | US | disclosed |