Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693990 | 0.89 | TNKS (0.49) | TNKSHSD17B10MAPTHPGDFEN1 | |
| SCHEMBL8696587 | 0.87 | HSD17B10 (0.60) | TNKSHSD17B10FEN1ALDH1A1PDE4A | |
| SCHEMBL8692400 | 0.86 | TNKS (0.50) | TNKSHSD17B10MAPTHPGDFEN1 | |
| SCHEMBL8695958 | 0.80 | ELANE (0.46) | TNKSHSD17B10FEN1ACVR1 | |
| SCHEMBL829613 | 0.79 | TNKS (0.52) | TNKSMAPTHPGDFEN1CYP3A4 | |
| SCHEMBL8693905 | 0.78 | PDE4A (0.45) | TNKSHSD17B10FEN1KDM4EALDH1A1 | |
| SCHEMBL8692208 | 0.78 | TNKS (0.47) | TNKSMAPTHPGDFEN1IDH1 | |
| SCHEMBL8691107 | 0.78 | BRD4 (0.52) | TNKSHSD17B10FEN1MEN1ACVR1 | |
| SCHEMBL830491 | 0.78 | TNKS (0.47) | TNKSMAPTHPGDFEN1CYP3A4 | |
| SCHEMBL8691820 | 0.78 | PIK3CD (0.51) | TNKSHSD17B10FEN1PDE4AACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |