Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 2/20 | 0.39 |
| ▸ | PRKCA | P17252 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829613 | 0.80 | TNKS (0.52) | TNKSFEN1GRM4BCL6MAPT | |
| SCHEMBL8695674 | 0.80 | BRD4 (0.48) | TNKSFEN1GRM4KDM4ECYP3A4 | |
| SCHEMBL8692400 | 0.79 | TNKS (0.50) | TNKSFEN1MAPTMEN1CYP1A2 | |
| SCHEMBL8693990 | 0.78 | TNKS (0.49) | TNKSFEN1GRM4MAPTMEN1 | |
| SCHEMBL8691823 | 0.78 | TNKS (0.52) | TNKSFEN1MAPTMEN1CYP1A2 | |
| SCHEMBL8696587 | 0.76 | HSD17B10 (0.60) | TNKSFEN1GRM4CYP2C19ALDH1A1 | |
| SCHEMBL8695958 | 0.75 | ELANE (0.46) | TNKSFEN1ACVR1ELANE | |
| SCHEMBL8693905 | 0.74 | PDE4A (0.45) | TNKSFEN1MEN1KMT2AKDM4E | |
| SCHEMBL8691107 | 0.74 | BRD4 (0.52) | TNKSFEN1PRKCAGSK3BMEN1 | |
| SCHEMBL8691820 | 0.74 | PIK3CD (0.51) | TNKSFEN1ACVR1ELANECDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |