Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.46 |
| ▸ | SRC | P12931 | 6/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749070 | 0.80 | CHRNB2 (0.68) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL3886866 | 0.79 | HTR6 (0.63) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL27683744 | 0.79 | HTR6 (0.50) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| Oxalic Acid SCHEMBL274980 | 0.78 | HTR6 (0.51) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL275390 | 0.77 | HTR6 (0.61) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL274981 | 0.77 | HTR6 (0.56) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL10965773 | 0.77 | KDM4E (0.52) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL7089878 | 0.77 | CHRNB2 (0.55) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL2403500 | 0.77 | KDM4E (0.59) | HTR6TSHRMEN1CYP1A2CYP3A4 | |
| SCHEMBL9300309 | 0.77 | HTR6 (0.49) | HTR6TSHRMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763471-A | TREATS PSYCHIATARIC AND BRAIN DISORDERS | CEMAF (FR) | 1998-06-09 | — | — | US | disclosed |