Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691915 | 0.92 | ADAM17 (0.46) | ADAM17LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8695152 | 0.92 | LPAR1 (0.46) | LPAR1LPAR5HDAC1HDAC6LMNA | |
| SCHEMBL8691477 | 0.87 | LPAR1 (0.45) | LPAR1LPAR5LMNAMAPTALOX12 | |
| SCHEMBL8498733 | 0.87 | LPAR1 (0.47) | ADAM17LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9114353 | 0.87 | LPAR1 (0.47) | ADAM17LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8498734 | 0.87 | LPAR1 (0.47) | ADAM17LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8695439 | 0.84 | LPAR1 (0.40) | LPAR1LPAR5 | |
| SCHEMBL8826200 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8826205 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8497073 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783593-A | FUNGICIDE; ANTICHOLESTEROL AGENT | ABBOTT LABORATORIES (US) | 1998-07-21 | — | — | US | disclosed |