Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862236 | 0.75 | NPC1 (0.54) | NPC1HSP90AA1L3MBTL1CCR1CCR8 | |
| SCHEMBL29511693 | 0.70 | NR4A2 (0.47) | NPC1HSP90AA1L3MBTL1CCR1CCR8 | |
| SCHEMBL8692881 | 0.70 | NR4A2 (0.47) | NPC1HSP90AA1L3MBTL1CCR1CCR8 | |
| SCHEMBL8117319 | 0.70 | L3MBTL1 (0.49) | NPC1HSP90AA1L3MBTL1APLNRCCR1 | |
| SCHEMBL26124342 | 0.69 | KDM4E (0.47) | HSP90AA1L3MBTL1APLNRKDM4EMAPT | |
| SCHEMBL31233897 | 0.69 | KDM4E (0.47) | HSP90AA1L3MBTL1APLNRKDM4EMAPT | |
| SCHEMBL31233902 | 0.69 | MAPT (0.47) | HSP90AA1L3MBTL1APLNRCCR1CCR8 | |
| SCHEMBL26121106 | 0.69 | MAPT (0.47) | HSP90AA1L3MBTL1APLNRCCR1CCR8 | |
| SCHEMBL6581851 | 0.68 | — | — | |
| SCHEMBL3969039 | 0.68 | ALDH1A1 (0.52) | NPC1HSP90AA1L3MBTL1CCR1CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804587-A | 6-(2-imidazolinylamino) quinolines useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1998-09-08 | — | — | US | disclosed |