Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26124342 | 1.00 | KDM4E (0.47) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL26121106 | 0.81 | MAPT (0.47) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL31233902 | 0.81 | MAPT (0.47) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL9654404 | 0.72 | MAPT (0.58) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL4726688 | 0.71 | ALDH1A1 (0.55) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL30387307 | 0.71 | KDM4E (0.62) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL4054902 | 0.71 | KDM4E (0.62) | KDM4EMAPTCYP3A4LMNAMEN1 | |
| SCHEMBL8692398 | 0.69 | NPC1 (0.41) | KDM4EMAPTHSP90AA1APLNRL3MBTL1 | |
| SCHEMBL383262 | 0.68 | GABRA1 (0.48) | CYP3A4ALDH1A1 | |
| SCHEMBL384468 | 0.68 | APLNR (0.43) | KDM4ELMNAAPLNRMPIL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118946553-A | SARM1 inhibitor compound, pharmaceutical composition comprising the same, and preparation method and use thereof | 深圳众格生物科技有限公司 | 2024-11-12 | — | — | CN | disclosed |