Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 4/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645143 | 0.91 | ALDH1A1 (0.39) | ITGB3ITGA2BALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8646612 | 0.90 | MEN1 (0.36) | ITGB3ITGA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL8646477 | 0.81 | ITGB3 (0.35) | ITGB3ITGA2BSMN1; SMN2GAANPC1 | |
| SCHEMBL8644292 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BALDH1A1F10PRSS1 | |
| SCHEMBL8646365 | 0.81 | ITGB3 (0.35) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL8643992 | 0.81 | ALDH1A1 (0.37) | ITGB3ITGA2BALDH1A1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL8646799 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1F10PRSS1 | |
| SCHEMBL8642859 | 0.79 | ITGB3 (0.40) | ITGB3ITGA2BF10F2TPSAB1 | |
| SCHEMBL8647512 | 0.78 | ITGB3 (0.36) | ITGB3ITGA2BALDH1A1TPSAB1TPSD1 | |
| SCHEMBL8644741 | 0.77 | ITGB3 (0.48) | ITGB3ITGA2BALDH1A1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |