Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062932 | 0.92 | SMN1; SMN2 (0.44) | KDM4ETDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7509440 | 0.85 | KDM4E (0.42) | KDM4EL3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL12590746 | 0.84 | SMN1; SMN2 (0.46) | KDM4ETDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL7498077 | 0.80 | AKR1B1 (0.41) | KDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12590776 | 0.77 | CYP1A2 (0.44) | TDP1L3MBTL1SMN1; SMN2HSD17B10TSHR | |
| SCHEMBL2063964 | 0.76 | MAPK1 (0.46) | KDM4ETDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL27284948 | 0.75 | MAPK1 (0.50) | KDM4ETDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL12651960 | 0.75 | MAPK1 (0.57) | KDM4ETDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL30959611 | 0.75 | SMN1; SMN2 (0.39) | L3MBTL1MAPK1SMN1; SMN2LMNAMEN1 | |
| SCHEMBL2062770 | 0.74 | ALDH1A1 (0.42) | KDM4EL3MBTL1SMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852023-A | Cyclohexylamino and cycloalkoxy nitrogen heterocycles, processes for their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-22 | — | — | US | disclosed |