Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31346908 | 0.85 | GAA (0.79) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL8694448 | 0.82 | KMT2A (0.68) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL15652679 | 0.82 | PTGDR2 (0.52) | ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL12479832 | 0.80 | KMT2A (0.73) | ALDH1A1KDM4EKMT2AMAPTGFER | |
| SCHEMBL29781911 | 0.80 | KMT2A (0.73) | ALDH1A1KDM4EKMT2AMAPTGFER | |
| SCHEMBL12479405 | 0.80 | LMNA (0.68) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL13675803 | 0.79 | LMNA (0.56) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL17995258 | 0.79 | NR4A2 (0.69) | ALDH1A1KMT2AMAPTNR4A2LMNA | |
| SCHEMBL17023509 | 0.78 | GAA (0.58) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL14876283 | 0.78 | ALDH1A1 (0.54) | ALDH1A1KDM4EKMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |