Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694236 | 0.96 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8695938 | 0.92 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8696191 | 0.90 | EPHX1 (0.47) | ALDH1A1KMT2AGAARAB9ALMNA | |
| SCHEMBL8696777 | 0.89 | POLB (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8694623 | 0.87 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8696343 | 0.86 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8698043 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8698386 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL8692678 | 0.85 | HTT (0.46) | ALDH1A1KMT2AGAAMAPTALOX12 | |
| SCHEMBL8698640 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |