Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694654 | 0.95 | KDM4E (0.39) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8693702 | 0.92 | KMT2A (0.42) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8698707 | 0.91 | GAA (0.44) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8693969 | 0.91 | HCAR2 (0.46) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8696801 | 0.87 | ALDH1A1 (0.43) | KDM4ESMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL8696838 | 0.87 | HCAR2 (0.44) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8693069 | 0.87 | KDM4E (0.41) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8698706 | 0.86 | HCAR2 (0.46) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8692678 | 0.86 | HTT (0.46) | GAAKDM4ESMN1; SMN2HPGDLMNA | |
| SCHEMBL8698640 | 0.86 | ALDH1A1 (0.41) | GAAKDM4ESMN1; SMN2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |