Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693176 | 0.92 | GAA (0.42) | KMT2AMAPTGAAALDH1A1CYP2C9 | |
| SCHEMBL8694003 | 0.91 | KMT2A (0.41) | KMT2AMAPTALOX12GAAALDH1A1 | |
| SCHEMBL8694654 | 0.90 | KDM4E (0.39) | GAAALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL8698706 | 0.89 | HCAR2 (0.46) | KMT2AMAPTALOX12GAAALDH1A1 | |
| SCHEMBL8696424 | 0.86 | SMN1; SMN2 (0.40) | KMT2AMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL8696733 | 0.86 | KMT2A (0.46) | KMT2AMAPTALOX12GAAALDH1A1 | |
| SCHEMBL8693579 | 0.85 | ALDH1A1 (0.43) | KMT2AMAPTALOX12GAAALDH1A1 | |
| SCHEMBL8698707 | 0.84 | GAA (0.44) | KMT2AMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL8693969 | 0.84 | HCAR2 (0.46) | KMT2AMAPTGAAALDH1A1CYP1A2 | |
| SCHEMBL8696838 | 0.82 | HCAR2 (0.44) | GAAALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |