Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.59 |
| ▸ | NPC1 | O15118 | 15/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 6/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499185 | 0.84 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL5733671 | 0.83 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL8695258 | 0.82 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL8690787 | 0.78 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL8690790 | 0.78 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL8693524 | 0.76 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL8693526 | 0.76 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL6506633 | 0.75 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL13405930 | 0.75 | HPGD (0.65) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL5866982 | 0.74 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843937-A | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents | PANORAMA RESEARCH, INC. (US) | 1998-12-01 | — | — | US | disclosed |