Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.56 |
| ▸ | NPC1 | O15118 | 14/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | TP53 | P04637 | 6/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | DDX3X | O00571 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690790 | 1.00 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8693526 | 0.89 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8693524 | 0.89 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8695258 | 0.87 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL24601168 | 0.82 | MAOB (0.63) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL5733671 | 0.81 | RAB9A (0.62) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL14499185 | 0.80 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL8693183 | 0.78 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2TP53PKM | |
| SCHEMBL7829761 | 0.76 | MMP13 (0.50) | RAB9ANPC1HPGDMEN1KMT2A | |
| SCHEMBL5866982 | 0.74 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843937-A | DNA-binding indole derivatives, their prodrugs and immunoconjugates as anticancer agents | PANORAMA RESEARCH, INC. (US) | 1998-12-01 | — | — | US | disclosed |