Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691611 | 0.96 | MCL1 (0.57) | MCL1ALDH1A1CYP1A2POLBTNF | |
| SCHEMBL7686010 | 0.95 | MCL1 (0.56) | MCL1ALDH1A1CYP1A2POLBTNF | |
| SCHEMBL6701625 | 0.92 | ALDH1A1 (0.59) | MCL1ALDH1A1CYP1A2POLBKDM4E | |
| SCHEMBL8653460 | 0.86 | KDM4E (0.64) | TNFKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL7686434 | 0.86 | PLA2G4A (0.46) | MCL1ALDH1A1CYP1A2POLBTNF | |
| SCHEMBL7256497 | 0.84 | MEN1 (0.63) | MCL1ALDH1A1CYP1A2POLBKDM4E | |
| SCHEMBL2480710 | 0.84 | ALDH1A1 (0.57) | MCL1ALDH1A1CYP1A2POLBCCR2 | |
| SCHEMBL8689867 | 0.83 | KDM4E (0.54) | TNFKDM4ECRHBPCRHR2SMN1; SMN2 | |
| SCHEMBL2015584 | 0.83 | SRD5A2 (0.63) | MCL1MEN1KMT2A | |
| SCHEMBL10757133 | 0.83 | ALDH1A1 (0.66) | MCL1ALDH1A1CYP1A2POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |