Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693185 | 0.86 | MCL1 (0.58) | GAATNFMCL1CTNNB1ALDH1A1 | |
| SCHEMBL7686577 | 0.85 | NOD2 (0.49) | GAATNFCTNNB1 | |
| SCHEMBL4370468 | 0.84 | ALDH1A1 (0.50) | PLA2G4AGAAMCL1GPR35LMNA | |
| SCHEMBL4363318 | 0.83 | PLA2G4A (0.52) | PLA2G4AGAAMCL1GPR35ALDH1A1 | |
| SCHEMBL8691611 | 0.83 | MCL1 (0.57) | GAATNFMCL1FAAHALDH1A1 | |
| SCHEMBL4361805 | 0.82 | PLA2G4A (0.53) | PLA2G4AGAAMCL1GPR35ALDH1A1 | |
| SCHEMBL7686010 | 0.82 | MCL1 (0.56) | TNFMCL1FAAHALDH1A1CYP1A2 | |
| SCHEMBL2015584 | 0.82 | SRD5A2 (0.63) | PLA2G4AMCL1 | |
| SCHEMBL13802535 | 0.82 | PLA2G4A (0.51) | PLA2G4AMCL1MAPTGPR35LMNA | |
| SCHEMBL9613337 | 0.79 | GPR35 (0.62) | MAPTGPR35LMNAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |