Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8693322 | 0.82 | KDM4E (0.40) | RAB9AMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL8691257 | 0.82 | KDM4E (0.40) | RAB9AMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL8692137 | 0.81 | MAPT (0.54) | RAB9AMAPTNPC1CASP3SENP8 | |
| SCHEMBL8312356 | 0.70 | ALDH1A1 (0.58) | RAB9AMAPTNPC1CASP3SENP8 | |
| SCHEMBL7558526 | 0.67 | NLRP3 (0.54) | RAB9ANPC1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL8688427 | 0.66 | RXFP1 (0.34) | RAB9ANPC1ALDH1A1HPGDTSHR | |
| SCHEMBL7562049 | 0.66 | KCNQ3 (0.45) | RAB9ANPC1ALDH1A1TSHRKDM4E | |
| SCHEMBL7554463 | 0.66 | PDE4A (0.44) | RAB9AMAPTNPC1ALDH1A1HPGD | |
| SCHEMBL6684298 | 0.66 | AGPAT2 (0.38) | RAB9AMAPTNPC1ALDH1A1KDM4E | |
| SCHEMBL8688388 | 0.66 | KDM4E (0.46) | RAB9AMAPTNPC1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753595-A | Herbicidal 3-(substituted benzoxazol-7-yl) and 3-(Substituted benzothiazol-7-yl)-1-substituted-6-trifluoromethyl-2 4-(1h 3h)pyrimidinediones | FMC CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| WO-1997008170-A1 | HERBICIDAL 3-(SUBSTITUTED BENZOXAZOL-7-YL) AND 3-(SUBSTITUTED BENZOTHIAZOL-7-YL)-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)PYRIMIDINEDIONES | FMC CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |