Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.51 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9148367 | 0.76 | SMN1; SMN2 (0.38) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL8690740 | 0.74 | ALDH1A1 (0.75) | ALDH1A1HPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL8312415 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL9147162 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1HPGDLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL8334566 | 0.73 | TLR8 (0.36) | ALDH1A1LMNASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8688371 | 0.72 | ALDH1A1 (0.44) | ALDH1A1HPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL8693243 | 0.70 | RAB9A (0.52) | ALDH1A1HPGDTSHRLMNASMN1; SMN2 | |
| SCHEMBL8331898 | 0.70 | KDR (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8329490 | 0.70 | TLR8 (0.40) | ALDH1A1SMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL8310400 | 0.70 | MAPT (0.36) | ALDH1A1LMNASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958295-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998033796-A1 | SUBSTITUTED 2-(2,4(1H,3H)-PYRIMIDINDION-3-YL) BENZTHIAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-06 | — | — | WO | disclosed |