Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070231 | 0.74 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6071345 | 0.74 | EPHX2 (0.55) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4248134 | 0.72 | LMNA (0.64) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL6070131 | 0.71 | KDM4E (0.47) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8693260 | 0.71 | ALDH1A1 (0.59) | MAPTKMT2AALDH1A1GAAHPGD | |
| SCHEMBL6071483 | 0.70 | CCR3 (0.60) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7402116 | 0.70 | HTT (0.45) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL3860597 | 0.70 | CACNA2D1 (0.61) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7405013 | 0.70 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL20561446 | 0.69 | KMT2A (0.55) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |