Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402116 | 0.88 | HTT (0.45) | ALDH1A1MEN1KMT2AHPGDLMNA | |
| SCHEMBL7288147 | 0.75 | CPA1 (0.53) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL6790329 | 0.73 | SMN1; SMN2 (0.59) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| Benzenemethanethiol SCHEMBL7371355 | 0.72 | USP2 (0.46) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7536026 | 0.72 | MMP8 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7536033 | 0.72 | MMP8 (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7278612 | 0.71 | HDAC3 (0.59) | ALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL2680002 | 0.71 | CPA3 (0.55) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9503176 | 0.71 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNASMN1; SMN2NPC1 | |
| SCHEMBL7596100 | 0.70 | MME (0.56) | ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280627-B1 | DERIVATIVES OF N-SUBSTITUTED ALPHA-MERCAPTOMETHYL-BENZENE-PROPANAMIDE, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-21 | — | — | EP | claimed |
| EP-0280627-B1 | DERIVATIVES OF N-SUBSTITUTED ALPHA-MERCAPTOMETHYL-BENZENE-PROPANAMIDE, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-04-21 | — | — | EP | disclosed |
| EP-0280627-A2 | Derivatives of N-substituted alpha-mercaptomethyl-benzene-propanamide, process for their preparation, their use as medicines and compositions containing them | ROUSSEL-UCLAF (FR) | 1988-08-31 | — | — | EP | disclosed |