Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY10 | O00398 | 7/20 | 0.53 |
| ▸ | GPR174 | Q9BXC1 | 7/20 | 0.53 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698834 | 0.99 | P2RY10 (0.51) | P2RY10GPR174PLA2G2CLPAR1LPAR3 | |
| SCHEMBL8695143 | 0.86 | P2RY10 (0.44) | P2RY10GPR174PLA2G2CLPAR1LPAR3 | |
| SCHEMBL8934957 | 0.82 | GPR174 (0.72) | P2RY10GPR174PLA2G2CLPAR5 | |
| SCHEMBL8692487 | 0.82 | P2RY10 (0.62) | P2RY10GPR174PLA2G2C | |
| SCHEMBL8935167 | 0.81 | GPR174 (0.71) | P2RY10GPR174PLA2G2CLPAR5 | |
| SCHEMBL8694073 | 0.81 | P2RY10 (0.60) | P2RY10GPR174PLA2G2C | |
| SCHEMBL9496438 | 0.78 | LPAR3 (0.56) | P2RY10PLA2G2CLPAR1LPAR3LPAR5 | |
| SCHEMBL31579146 | 0.77 | LPAR3 (0.61) | PLA2G2CLPAR1LPAR3LPAR5USP2 | |
| SCHEMBL8722280 | 0.76 | PLA2G2C (0.66) | P2RY10PLA2G2CLPAR1LPAR3LPAR5 | |
| SCHEMBL8724394 | 0.76 | LPAR3 (0.60) | PLA2G2CLPAR1LPAR3LPAR5USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804552-A | COMPOUND CONSISTING OF TYROSINE OR HYDROXYPROLINE LINKED TO PHOSPHOLIPID BY PHOSPHOESTER BOND THROUGH HYDROXYL GROUP; CAPABLE OF CONJUGATION WITH THERAPEUTIC PEPTIDE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| US-5554728-A | Lipid conjugates of therapeutic peptides and protease inhibitors | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-09-10 | — | — | US | disclosed |