Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NAMPT | P43490 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8593357 | 0.90 | ALDH1A1 (0.48) | MAPTNAMPTALDH1A1LMNAKDM4E | |
| SCHEMBL8696343 | 0.89 | ALDH1A1 (0.47) | MAPTNAMPTALDH1A1LMNAKDM4E | |
| SCHEMBL8698039 | 0.88 | ADORA3 (0.52) | MAPTNAMPTALDH1A1LMNAKDM4E | |
| SCHEMBL8696823 | 0.88 | ALDH1A1 (0.46) | MAPTNAMPTALDH1A1LMNAKDM4E | |
| SCHEMBL8696191 | 0.87 | EPHX1 (0.47) | ALDH1A1LMNAKDM4EGAAKLKB1 | |
| SCHEMBL8693518 | 0.86 | EGFR (0.54) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL8693623 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL8698728 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAKDM4EGAA | |
| SCHEMBL8693064 | 0.85 | ALDH1A1 (0.52) | MAPTALDH1A1LMNAKDM4EKLKB1 | |
| SCHEMBL8696320 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAKDM4EPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849779-A | Pyrazole derivatives and their pharmaceutical use | JAPAN ENERGY CORPORATION (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0810217-A1 | Pyrazole derivatives and their pharmaceutical use as smooth muscle cell growth inhibitors | JAPAN ENERGY CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |