Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxatomide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.98 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.98 |
| ▸ | LMNA | P02545 | 2/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | MLNR | O43193 | 1/20 | 0.98 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.98 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.98 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.98 |
| ▸ | DRD2 | P14416 | 1/20 | 0.98 |
| ▸ | PKM | P14618 | 1/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.98 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.98 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.98 |
| ▸ | HTR2A | P28223 | 1/20 | 0.98 |
| ▸ | HTR2C | P28335 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxatomide SCHEMBL11472510 | 1.00 | P2RX7 (0.98) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Oxatomide SCHEMBL8693540 | 1.00 | P2RX7 (0.98) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Oxatomide SCHEMBL11199692 | 0.99 | P2RX7 (0.95) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Oxatomide SCHEMBL28824 | 0.99 | P2RX7 (1.00) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Oxatomide SCHEMBL29484467 | 0.99 | P2RX7 (1.00) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Oxatomide SCHEMBL7558760 | 0.98 | P2RX7 (0.98) | P2RX7LMNAMEN1MLNRNR1I2 | |
| SCHEMBL11198903 | 0.96 | P2RX7 (1.00) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Hydrochloric Acid SCHEMBL11195765 | 0.95 | P2RX7 (0.96) | P2RX7LMNAMEN1MLNRNR1I2 | |
| SCHEMBL11195898 | 0.95 | P2RX7 (1.00) | P2RX7LMNAMEN1MLNRNR1I2 | |
| Water SCHEMBL11197270 | 0.95 | P2RX7 (0.98) | P2RX7LMNAMEN1MLNRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998058924-A1 | A PROCESS FOR THE PREPARATION OF OXATOMIDE | BIDACHEM S.P.A. (IT) | 1998-12-30 | — | — | WO | disclosed |