Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697838 | 0.90 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3EPHX1MEN1 | |
| SCHEMBL8689640 | 0.85 | MAOA (0.36) | SLC6A2SLC6A4SLC6A3MAOATHRA | |
| SCHEMBL8697815 | 0.75 | PTGS2 (0.36) | SLC6A2SLC6A4SLC6A3MAOATHRA | |
| SCHEMBL30937471 | 0.69 | HDAC1 (0.48) | EPHX1BCHEMAPTTDP1NPSR1 | |
| SCHEMBL2307317 | 0.69 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3BCHEMAPT | |
| SCHEMBL7214903 | 0.66 | L3MBTL1 (0.49) | KDM4EMAPTTDP1 | |
| SCHEMBL29792562 | 0.66 | L3MBTL1 (0.49) | KDM4EMAPTTDP1 | |
| SCHEMBL10631836 | 0.66 | PTGS2 (0.47) | SLC6A2SLC6A4SLC6A3MAOAGAA | |
| SCHEMBL9913545 | 0.65 | KDM4A (0.40) | SLC6A2SLC6A4SLC6A3TACR1BCHE | |
| SCHEMBL13539191 | 0.65 | KDM4A (0.43) | SLC6A2SLC6A4SLC6A3TACR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |