SCHEMBL86953

SCHEMBL86953

C=CC(=O)Oc1ccc2c(c1)C(=O)c1ccccc1OC2

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.62
ALDH1A1 P00352 4/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
KMT2A Q03164 2/20 0.59
RAB9A P51151 2/20 0.53
KDM4E B2RXH2 1/20 0.53
NPC1 O15118 1/20 0.53
GAA P10253 1/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
AKR1B1 P15121 1/20 0.44
MAOB P27338 4/20 0.42
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10922096 0.86 MAPT (0.70) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL87291 0.82 MAPT (0.50) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL86318 0.79 ALDH1A1 (0.82) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL12216194 0.78 MAPT (0.49) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL23963396 0.78 MAOA (0.51) MAPTALDH1A1SMN1; SMN2KMT2AKDM4E
SCHEMBL3809960 0.77 ALDH1A1 (1.00) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL10925574 0.77 MAPT (0.85) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL2814971 0.77 TTR (0.46) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL10922029 0.74 TTR (0.55) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A
SCHEMBL86392 0.73 MAPT (0.67) MAPTALDH1A1SMN1; SMN2KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2053095-B1 Ink composition and inkjet recording method using the same FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-8129447-B2 Ink composition and inkjet recording method using the same FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
EP-2053095-A2 Ink composition and inkjet recording method using the same Fujifilm Corporation (JP) 2009-04-29 EP disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087575-A1 INK COMPOSITION AND INKJET RECORDING METHOD USING THE SAME RB1, IK, NOX1 MAPT 2087/4885ALDH1A1 440/4885SMN1; SMN2 2151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.