Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.45 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.35 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.35 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL8695387 | 0.94 | PDCD1LG2 (0.44) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 | |
| Asparagine SCHEMBL8695366 | 0.94 | PDCD1LG2 (0.44) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 | |
| Asparagine SCHEMBL27468642 | 0.88 | CD274 (0.40) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 | |
| Asparagine SCHEMBL1964053 | 0.87 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Asparagine SCHEMBL9695773 | 0.87 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Asparagine SCHEMBL1964050 | 0.87 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Asparagine SCHEMBL7763890 | 0.87 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL2722186 | 0.86 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 | |
| Glutamine SCHEMBL1403799 | 0.85 | ALOX15 (0.54) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 | |
| Glutamine SCHEMBL1403796 | 0.85 | ALOX15 (0.54) | SLC7A5SLC1A3SLC1A2PDCD1LG2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728482-A2 | Use of hcp specific compounds to enhance erythropoiesis | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-28 | — | — | EP | disclosed |
| EP-0727211-A1 | Use of src SH2 specific compounds to treat a bone resorption disease | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-21 | — | — | EP | disclosed |