Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697753 | 0.86 | EPHX1 (0.33) | MME | |
| SCHEMBL27889030 | 0.83 | MME (0.49) | PPARAMEN1KMT2AMMETAAR1 | |
| SCHEMBL8694913 | 0.82 | MAOA (0.38) | MAOBMMEMAOA | |
| SCHEMBL8694883 | 0.80 | SLC1A1 (0.51) | SLC1A1PPARGPPARAMEN1KMT2A | |
| SCHEMBL8861583 | 0.80 | SLC1A1 (0.51) | SLC1A1PPARGPPARAMEN1KMT2A | |
| SCHEMBL8695484 | 0.78 | SLC1A1 (0.44) | SLC1A1MAOBPPARGPPARAMEN1 | |
| SCHEMBL8702373 | 0.75 | SLC1A1 (0.44) | SLC1A1MAOBPPARGPPARAHCAR2 | |
| SCHEMBL8695470 | 0.75 | SRR (0.42) | PPARGPPARAMME | |
| SCHEMBL19812679 | 0.73 | TAAR1 (0.50) | SLC1A1MAOBPPARGPPARAHCAR2 | |
| SCHEMBL8692220 | 0.72 | LDHA (0.50) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846956-A | Amino acids derivatives, the process for their preparation and their applications to therapy | SOCIETE CIVILE BIOPROJET (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5670531-A | ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS | SOCIETE CIVILE BIOPROJET (FR) | 1997-09-23 | — | — | US | disclosed |