Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3452908 | 0.79 | LMNA (0.80) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL12595833 | 0.77 | LMNA (0.50) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL12595747 | 0.77 | LMNA (0.50) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL12595816 | 0.76 | LMNA (0.51) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL12692666 | 0.75 | ALK (0.48) | LMNAMEN1KMT2APDE3BPDE3A | |
| SCHEMBL1769796 | 0.74 | NOTUM (0.61) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL13071050 | 0.74 | NOTUM (0.61) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL7277959 | 0.74 | PDE3B (0.68) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL7279874 | 0.74 | PDE3A (0.68) | HRH3LMNAMEN1KMT2APDE3B | |
| SCHEMBL7319085 | 0.73 | PDE3B (0.67) | HRH3LMNAMEN1KMT2APDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789402-A | Compounds having effects on serotonin-related systems | ELI LILLY COMPANY (US) | 1998-08-04 | — | — | US | disclosed |
| US-5741789-A | HETERO-OXY ALKANAMINES | ELI LILLY AND COMPANY (US) | 1998-04-21 | — | — | US | disclosed |