Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.42 |
| ▸ | CASP7 | P55210 | 4/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517807 | 0.83 | ELANE (0.53) | ELANEBRD4CLK4HSD17B10CYP1A2 | |
| SCHEMBL8695958 | 0.82 | ELANE (0.46) | ELANEHSD17B10 | |
| SCHEMBL8696587 | 0.82 | HSD17B10 (0.60) | BRD4HSD17B10ALDH1A1TSHR | |
| SCHEMBL8691820 | 0.81 | PIK3CD (0.51) | ELANEHSD17B10TGFBR1 | |
| SCHEMBL8693905 | 0.81 | PDE4A (0.45) | HSD17B10TGFBR1ALDH1A1MEN1KMT2A | |
| SCHEMBL8691107 | 0.81 | BRD4 (0.52) | ELANEBRD4HSD17B10MEN1 | |
| SCHEMBL8692400 | 0.81 | TNKS (0.50) | HSD17B10CYP1A2MEN1HPGDKMT2A | |
| SCHEMBL8694011 | 0.79 | BRD4 (0.54) | BRD4CLK4HSD17B10MEN1KMT2A | |
| SCHEMBL8696634 | 0.78 | GRIN1 (0.47) | HSD17B10TGFBR1 | |
| SCHEMBL8693665 | 0.77 | MET (0.51) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817670-A | RESPIRATORY SYSTEM DISORDERS, ORGAN TRANSPLANTATION, ANTITUMOR AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-10-06 | — | — | US | disclosed |
| EP-0779292-A1 | NOVEL NAPHTHYRIDINE DERIVATIVE AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-06-18 | — | — | EP | disclosed |