Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962097 | 0.89 | HDAC8 (0.68) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL21582596 | 0.86 | CTSK (0.68) | CTSKCTSSSCN9APPARGPPARA | |
| SCHEMBL7722248 | 0.84 | CTSK (0.62) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL16006047 | 0.84 | CTSK (0.57) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL13669553 | 0.84 | CTSS (0.74) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL6550878 | 0.84 | CTSS (0.74) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL12890034 | 0.84 | CTSS (0.74) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL7728624 | 0.83 | CTSK (0.64) | CTSKCTSSHDAC8HDAC4HDAC1 | |
| SCHEMBL8239150 | 0.83 | PPARA (0.64) | CTSKCTSSPPARGPPARAKMT2A | |
| SCHEMBL12305803 | 0.83 | PPARA (0.64) | CTSKCTSSPPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |