Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 4/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7840898 | 0.85 | TOP2A (0.52) | TOP2ATOP2BPOLBKDM4EALDH1A1 | |
| SCHEMBL7842470 | 0.83 | ADRB2 (0.34) | ADRB2TOP2ATOP2BPOLBALDH1A1 | |
| SCHEMBL8692136 | 0.83 | ADRB2 (0.47) | ADRB2STAT3TOP2ATOP2BTDP1 | |
| SCHEMBL9133982 | 0.82 | ADRB2 (0.50) | ADRB2STAT3TOP2ATOP2BTSHR | |
| SCHEMBL8116592 | 0.80 | ADRB2 (0.49) | ADRB2STAT3TOP2ATOP2BTSHR | |
| SCHEMBL9585893 | 0.79 | STAT3 (0.54) | ADRB2STAT3TOP2ATOP2BTSHR | |
| SCHEMBL5704330 | 0.79 | ADRB2 (0.49) | ADRB2STAT3TOP2ATOP2BTSHR | |
| SCHEMBL9688633 | 0.79 | CACNA1F (0.49) | ADRB2STAT3TOP2ATOP2BPOLB | |
| SCHEMBL8696955 | 0.79 | STAT3 (0.43) | STAT3TDP1TSHRCASP1POLB | |
| SCHEMBL7840900 | 0.78 | TOP2A (0.37) | TOP2ATOP2BPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811433-A | ANTIMICROBIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-22 | — | — | US | disclosed |