Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696137 | 0.79 | MEN1 (0.38) | PTGESALOX5ALDH1A1MAPTKDM4E | |
| SCHEMBL6983626 | 0.73 | HDAC1 (0.48) | HDAC1 | |
| SCHEMBL7970722 | 0.65 | TRPM8 (0.42) | ALOX5LMNAHDAC1TRPM8 | |
| SCHEMBL17776389 | 0.65 | CHRNB2 (0.44) | KDM4EGAAHDAC1TRPM8 | |
| SCHEMBL3051043 | 0.62 | ADRB2 (0.37) | ALDH1A1KDM4ETP53SMN1; SMN2 | |
| SCHEMBL29913609 | 0.60 | TRPM8 (0.39) | ALDH1A1GAALMNAHDAC1SMN1; SMN2 | |
| SCHEMBL7636101 | 0.60 | KDM4E (0.49) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL23609358 | 0.60 | S1PR3 (0.32) | KMT2AGABRB1GABRB2 | |
| SCHEMBL7408450 | 0.60 | GAA (0.44) | KDM4EGAA | |
| SCHEMBL31016664 | 0.60 | GAA (0.44) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |