Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696194 | 1.00 | CTSS (0.53) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL17713403 | 0.91 | CTSK (0.55) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL17713402 | 0.91 | CTSK (0.55) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL7370522 | 0.89 | CTSK (0.57) | CTSSCTSKPPARACTSLPPARG | |
| SCHEMBL8698935 | 0.89 | CTSK (0.57) | CTSSCTSKPPARACTSLPPARG | |
| SCHEMBL3881683 | 0.88 | CTSS (0.65) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL8696309 | 0.88 | CTSS (0.65) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL8062883 | 0.88 | CTSS (0.65) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL7491530 | 0.86 | CACNA1B (0.47) | CTSSCTSKSYKPPARACTSL | |
| SCHEMBL8699827 | 0.85 | CTSL (0.52) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |