Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512121 | 0.78 | CYP1A2 (0.45) | MAOAANPEP | |
| SCHEMBL2269387 | 0.77 | GFER (0.42) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL242930 | 0.77 | GFER (0.42) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL242929 | 0.77 | GFER (0.42) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8696253 | 0.75 | TSHR (0.41) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11847632 | 0.73 | GFER (0.48) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL7794645 | 0.71 | LOXL2 (0.40) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL18789242 | 0.69 | ALDH1A1 (0.55) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL10954821 | 0.69 | MAPT (0.40) | GFERALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL1048212 | 0.67 | ALDH1A1 (0.52) | GFERALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741781-A | NEUTRAL ENDOPEPTIDASE AND ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | ADIR ET COMPAGNIE (FR) | 1998-04-21 | — | — | US | disclosed |