Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812641 | 0.83 | EPHX1 (0.43) | LOXL2ALDH1A1ANPEPMAOA | |
| SCHEMBL19812643 | 0.74 | TAAR1 (0.47) | ALDH1A1DPP4DPP8DPP9MAPT | |
| SCHEMBL9542370 | 0.73 | HTR2A (0.46) | LOXL2MAOA | |
| SCHEMBL2269387 | 0.72 | GFER (0.42) | LOXL2GFERALDH1A1CYP3A4TSHR | |
| SCHEMBL242929 | 0.72 | GFER (0.42) | LOXL2GFERALDH1A1CYP3A4TSHR | |
| SCHEMBL242930 | 0.72 | GFER (0.42) | LOXL2GFERALDH1A1CYP3A4TSHR | |
| SCHEMBL8696247 | 0.71 | GFER (0.41) | LOXL2GFERALDH1A1CYP3A4TSHR | |
| SCHEMBL5321900 | 0.70 | — | — | |
| SCHEMBL19812666 | 0.67 | EPHX1 (0.46) | LOXL2ANPEPMAOA | |
| SCHEMBL5049235 | 0.67 | EPHX1 (0.46) | LOXL2ANPEPMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010020040-A1 | Hyperforin derivatives, use thereof and formulations containing them | INDENA S.P.A. (IT) | 2001-09-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020040-A1 | Hyperforin derivatives, use thereof and formulations containing them | CRH, FOS, VIP | LOXL2 4305/4885GFER 3629/4885ALDH1A1 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.