Glycitein

Glycitein

SCHEMBL869704

COc1cc2c(=O)c(-c3ccc(O)cc3)coc2cc1O.O=c1c(-c2ccccc2)coc2ccccc12

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.83
RAB9A P51151 6/20 0.70
KLK7 P49862 1/20 0.70
PPARG P37231 2/20 0.68
PTPN1 P18031 1/20 0.68
KDM4E B2RXH2 9/20 0.62
MAPT P10636 6/20 0.62
NPC1 O15118 5/20 0.62
POLB P06746 3/20 0.62
HMGB1 P09429 1/20 0.62
ALOX15 P16050 2/20 0.60
ALOX12 P18054 1/20 0.60
XDH P47989 1/20 0.60
ALDH1A1 P00352 7/20 0.59
SMN1; SMN2 Q16637 6/20 0.59
NPSR1 Q6W5P4 1/20 0.59
HSD17B10 Q99714 5/20 0.57
TP53 P04637 4/20 0.57
MAPK1 P28482 1/20 0.57
HPGD P15428 5/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycitein SCHEMBL19720 0.91 HDAC6 (1.00) HDAC6RAB9AKLK7PPARGPTPN1
Glycitein SCHEMBL7733712 0.91 HDAC6 (1.00) HDAC6RAB9AKLK7PPARGPTPN1
SCHEMBL5426172 0.91 HDAC6 (0.81) HDAC6RAB9AKLK7PPARGPTPN1
Glycitein SCHEMBL29497281 0.91 HDAC6 (1.00) HDAC6RAB9AKLK7PPARGPTPN1
Glycitein SCHEMBL4725635 0.91 HDAC6 (0.78) HDAC6RAB9AKLK7PPARGPTPN1
Glycitein SCHEMBL5483545 0.89 HDAC6 (0.91) HDAC6RAB9AKLK7PPARGPTPN1
Isoflavone SCHEMBL3066716 0.87 ALOX12 (0.80) HDAC6RAB9APPARGKDM4EMAPT
SCHEMBL11336575 0.86 HDAC6 (0.90) HDAC6RAB9AKLK7PPARGPTPN1
Glycitein SCHEMBL6578666 0.85 RAB9A (0.85) HDAC6RAB9AKLK7PPARGPTPN1
SCHEMBL11344171 0.84 HDAC6 (0.85) HDAC6RAB9AKLK7PPARGPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060073250-A1 Continuous adsorption process for the preparation of a soy protein-containing composition having improved flavor, odor, appearance, or functionality SOLAE, LLC. 2006-04-06 US claimed
US-20060062889-A1 Soy protein-containing composition SOLAE, LLC. 2006-03-23 US claimed
US-20060062878-A1 Size exclusion chromatography process for the preparation of an improved soy protein-containing composition SOLAE, LLC 2006-03-23 US claimed
EP-1038531-A2 A composition comprising soybean isoflavones and a method for the production thereof Ajinomoto Co., Inc. (JP) 2000-09-27 EP claimed
US-20170156388-A1 NUTRIENT DELIVERY SYSTEM ABBOTT LABORATORIES (US) 2017-06-08 US disclosed
EP-3171741-A1 NUTRIENT DELIVERY SYSTEM Abbott Laboratories (US) 2017-05-31 EP disclosed
WO-2016014519-A1 NUTRIENT DELIVERY SYSTEM ABBOTT LABORATORIES (US) 2016-01-28 WO disclosed
US-20140057005-A1 DEVELOPMENT OF A PYTOESTROGEN PRODUCT FOR THE PREVENTION OR TREATMENT OF OSTEOPOROSIS USING RED CLOVER TAM YUN KAU (CA) 2014-02-27 US disclosed
US-20120077874-A1 DEVELOPMENT OF A PHYTOESTROGEN PRODUCT FOR THE PREVENTION OR TREATMENT OF OSTEOPOROSIS USING RED CLOVER TAM YUN KAU (CA) 2012-03-29 US disclosed
US-7169425-B2 Size exclusion chromatography process for the preparation of an improved soy protein-containing composition SOLAE, LLC (US) 2007-01-30 US disclosed
US-20060073250-A1 Continuous adsorption process for the preparation of a soy protein-containing composition having improved flavor, odor, appearance, or functionality SOLAE, LLC. 2006-04-06 US disclosed
US-20060062889-A1 Soy protein-containing composition SOLAE, LLC. 2006-03-23 US disclosed
US-20060062878-A1 Size exclusion chromatography process for the preparation of an improved soy protein-containing composition SOLAE, LLC 2006-03-23 US disclosed
EP-1038531-A2 A composition comprising soybean isoflavones and a method for the production thereof Ajinomoto Co., Inc. (JP) 2000-09-27 EP disclosed