Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.91 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.78 |
| ▸ | RAB9A | P51151 | 6/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | NPC1 | O15118 | 5/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.78 |
| ▸ | KLK7 | P49862 | 1/20 | 0.76 |
| ▸ | PPARG | P37231 | 4/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.72 |
| ▸ | HPGD | P15428 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | MAOA | P21397 | 3/20 | 0.72 |
| ▸ | MAOB | P27338 | 3/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycitein SCHEMBL6578666 | 0.96 | RAB9A (0.85) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL29497281 | 0.95 | HDAC6 (1.00) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL19720 | 0.95 | HDAC6 (1.00) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL7733712 | 0.95 | HDAC6 (1.00) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL8065644 | 0.93 | HDAC6 (0.78) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL11336575 | 0.90 | HDAC6 (0.90) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL3928329 | 0.89 | HDAC6 (0.83) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Glycitein SCHEMBL869704 | 0.89 | HDAC6 (0.83) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| SCHEMBL2069826 | 0.88 | KDM4E (0.84) | HDAC6KDM4ERAB9AMAPTNPC1 | |
| Calycosin SCHEMBL73013 | 0.88 | KDM4E (1.00) | HDAC6KDM4ERAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208594-B2 | Isoflavone concentrates as well as methods for their production | AQUANOVA AG (DE) | 2007-04-24 | — | — | US | claimed |
| US-5990291-A | MIXTURE OF AT LEAST TWO ISOFLAVONES WHICH ARE WATER INSOLUBLE AT TEMPERATURE FROM 0 TO 35 DEGREES CELSIUS; ANTICARCINOGENIC AGENTS; TREATMENT OF MENOPAUSE, PREMENSTRUAL TENSION, AND CARDIOVASCULAR DISORDERS | PROTEIN TECHNOLOGIES INTERNATIONAL, INC. (US) | 1999-11-23 | — | — | US | disclosed |