Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 4/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | TYR | P14679 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697176 | 0.88 | EPHX2 (0.56) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL19504285 | 0.88 | EPHX2 (0.68) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL15111041 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2GAAGLO1 | |
| SCHEMBL15111043 | 0.86 | KDM4E (0.71) | KDM4EALDH1A1SMN1; SMN2GAAGLO1 | |
| SCHEMBL13070900 | 0.85 | GLO1 (0.55) | FDPSKDM4EALDH1A1MAPTSMN1; SMN2 | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411956 | 0.84 | FDPS (0.80) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| Methyl Cis-3,4-Dimethoxycinnamate SCHEMBL2411955 | 0.84 | FDPS (0.80) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL9397987 | 0.81 | EPHX2 (0.77) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL8320184 | 0.81 | EPHX2 (0.77) | EPHX2FDPSKDM4EALDH1A1MAPT | |
| SCHEMBL10951487 | 0.81 | EPHX2 (0.68) | EPHX2FDPSKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756527-A | ANTICARCINOGENIC AGENTS | ONTOGEN CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0812830-A1 | Modulators of multi-drug resistances | ONTOGEN CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |