Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959296 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HRH3 | |
| SCHEMBL11210909 | 0.73 | KDM4E (0.40) | ALDH1A1LMNAKDM4ETP53L3MBTL1 | |
| SCHEMBL16015681 | 0.69 | ALDH1A1 (0.46) | ALDH1A1LMNAKDM4ECYP3A4KMT2A | |
| SCHEMBL8416472 | 0.68 | KDM4E (0.61) | LMNAKDM4E | |
| SCHEMBL3757039 | 0.68 | LMNA (0.74) | ALDH1A1LMNAKDM4ETP53L3MBTL1 | |
| SCHEMBL13202553 | 0.67 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL5374196 | 0.66 | KMT2A (0.41) | ALDH1A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL5374192 | 0.66 | KMT2A (0.41) | ALDH1A1LMNAKDM4ETSHRHPGD | |
| SCHEMBL5375109 | 0.66 | PDE10A (0.39) | ALDH1A1LMNAKMT2A | |
| SCHEMBL23828671 | 0.64 | HRH3 (0.69) | ALDH1A1LMNAL3MBTL1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |