Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.40 |
| ▸ | SI | P14410 | 2/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25239708 | 0.83 | TDP1 (0.70) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL9458220 | 0.81 | ALDH1A1 (0.57) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL2954856 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TDP1HSD17B10ADAMTS4PTPN1 | |
| SCHEMBL2958562 | 0.80 | ALDH1A1 (0.92) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| Benzene SCHEMBL28038982 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL44392 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL30196067 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL9589260 | 0.79 | ALDH1A1 (0.59) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL7821087 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 | |
| SCHEMBL6747891 | 0.78 | ALDH1A1 (0.74) | ALDH1A1TDP1HSD17B10ADAMTS4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |