Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KAT7 | O95251 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697217 | 0.81 | PSMB8 (0.50) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8698930 | 0.79 | PSMB8 (0.43) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8701281 | 0.74 | PSMB8 (0.64) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8698994 | 0.74 | PSMB8 (0.64) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8698563 | 0.72 | BRD4 (0.38) | KDM4EALDH1A1MAPTHTTPKM | |
| SCHEMBL8703017 | 0.71 | PSMB8 (0.46) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL13508871 | 0.70 | PSMB8 (0.61) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8704890 | 0.69 | PSMB8 (0.53) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL15709920 | 0.69 | AHR (0.54) | KDM4EALDH1A1MAPTBRD4TDP1 | |
| SCHEMBL8698519 | 0.68 | PSMB8 (0.45) | PSMB8KDM4EGAAALDH1A1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |