Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 6/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 6/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 6/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 6/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 6/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 6/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | RORA | P35398 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | RORB | Q92753 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517524 | 1.00 | PSEN1 (0.52) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14976913 | 0.98 | PGR (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11142970 | 0.94 | PGR (0.56) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19179335 | 0.90 | PGR (0.51) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL974629 | 0.86 | PGR (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6575875 | 0.86 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1001993 | 0.86 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL750975 | 0.86 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL1000878 | 0.86 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL6774209 | 0.86 | PGR (0.64) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708178-A | Thermally stable electro-optic device and method | LOCKHEED MARTIN CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| US-5561733-A | ACCEPTOR-DONOR-ACCEPTOR OR DONOR-ACCEPTOR-DONOR GUEST DIPOLE COMPOUNDS IN A TEMPERATURE-RESISTANCE POLYMER MATRIX | LOCKHEAD MISSILES & SPACE COMPANY, INC. (US) | 1996-10-01 | — | — | US | disclosed |